Przeciwwirusowe działanie triterpenoidów roślinnych

Abstrakt

One of the most interesting groups of secondary plant compounds are penta- and tetracyclic triterpenoids and their glycosides and glycosidoesters. They have a wide spectrum of pharmaceutical activities such as anti-inflammatory, anti-tumor, anti-mutagenic, cytotoxic, anti-hepatotoxic, anti-diabetic, antibacterial etc. This review summarises studies on antiviral activity of triterpenoids and their natural and synthetic derivatives. Possible mechanisms of pharmacological effects on human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1) as well as the prospects for future applications of these compounds are discussed.